Homeostasis:- From the earliest days of physiology—at least as early as the time of Aristotle—physicians recognized that good health was somehow associated with a balance among the multiple lifesustaining forces (“humours”) in the body. It was further determined by careful observation that most of the common physiological variables found in healthy organisms such as humans—blood pressure; body temperature; and blood-borne factors such as oxygen, glucose, and sodium ions, for example—are maintained within a predictable range. This is true despite external environmental conditions that may be far from constant. Thus was born the idea, first put forth by Claude Bernard , of a constant internal environment that is a prerequisite for good health, a concept later refined by the American physiologist Walter Cannon, who coined the term homeostasis . Originally, Homeostasis was defined as a state of reasonably stable balance between physiological variables such as those just descr
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